منابع مشابه
Oral Antidiabetic Sulfonamides
In October 1955 three reports in the Deutsche Medizinische Wochenschrift' described a new sulfonamide derivative possessing the ability when given by mouth to reduce normal blood sugar values to subnormal, and elevated blood and urine sugar values in diabetes to normal. Reduction of normoglycemia had been shown with other sulfonamide derivatives as early as 1942," but the application to therapy...
متن کاملPharmacogenetics of Oral Antidiabetic Drugs
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register studies, but only a handful of associations detected in these studies were replicated. The gene variants in CYP2C9, ABCC8/KCNJ11, and TCF7L2 w...
متن کاملOral Antidiabetic Drugs for Cats
Diabetes mellitus (DM) is commonly diagnosed in cats. In humans, treatment regimens for non–insulin-dependent DM include various combinations of dietary modification, exercise, insulin administration, and one or more oral antidiabetic drugs, which have been extensively evaluated in humans but not in cats. Glucose toxicity is a phenomenon of chronic hyperglycemia and must be understood before in...
متن کاملCardiovascular Safety of Oral Antidiabetic Drugs
SAŽETAK: Hrvatska pripada skupini europskih zemalja s visokim kardiovaskularnim rizikom i rastućom prevalencijom šećerne bolesti tipa 2 (DMT2). Prema podatcima Nacionalnog registra osoba sa šećernom bolešću (CroDiab registar), u Hrvatskoj je 2014. godine bilo evidentirano ukupno 254 296 osoba oboljelih od dijabetesa starijih od 18 godina (7,9 %). DMT2 je, uz hipertenziju i hiperlipidemiju, jeda...
متن کاملTEACHERS’ TOPICS Insulin and Oral Antidiabetic Agents
The current manuscript describes an overview for therapeutic approaches to treat diabetes mellitus. Detailed presentation of the role of insulin in both disease state development and therapy is given. The article also addresses the classification, chemistry, pharmacokinetic properties, dosage forms, mechanisms of action, and therapeutic indications of oral anti-diabetic agents currently availab...
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ژورنال
عنوان ژورنال: Diabetes
سال: 1956
ISSN: 0012-1797,1939-327X
DOI: 10.2337/diab.5.1.62